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Article Dans Une Revue Comptes Rendus Biologies Année : 2015

Enzymatic cybernetics: An unpublished work by Jacques Monod

Résumé

In 1959, Jacques Monod wrote a manuscript entitled Cybernétique enzymatique [Enzymatic cybernetics]. Never published, this unpublished manuscript presents a synthesis of how Monod interpreted enzymatic adaptation just before the publication of the famous papers of the 1960s on the operon. In addition, Monod offers an example of a philosophy of biology immersed in scientific investigation. Monod's philosophical thoughts are classified into two categories, methodological and ontological. On the methodological side, Monod explicitly hints at his preferences regarding the scientific method in general: hypothetical-deductive method, and use of theoretical models. He also makes heuristic proposals regarding molecular biology: the need to analyse the phenomena in question at the level of individual cells, and the dual aspect of all biological explanation, functional and evolutionary. Ontological issues deal with the notions of information and genetic determinism, “cellular memory”, the irrelevance of the notion of “living matter”, and the usefulness of a cybernetic comprehension of molecular biology.

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Philosophie
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Dates et versions

halshs-01164396 , version 1 (17-06-2015)

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Jean Gayon. Enzymatic cybernetics: An unpublished work by Jacques Monod. Comptes Rendus Biologies, 2015, Jacques Monod – A theorist in the era of molecular biology, 338, pp.398-405. ⟨10.1016/j.crvi.2015.04.007⟩. ⟨halshs-01164396⟩
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