Profile order and time-dependent artifacts in contrast-enhanced coronary MR angiography at 3T: origin and prevention. - DyCTim : Dynamique Cellulaire / Tissulaire et Microscopie fonctionnelle Accéder directement au contenu
Article Dans Une Revue Magnetic Resonance in Medicine Année : 2009

Profile order and time-dependent artifacts in contrast-enhanced coronary MR angiography at 3T: origin and prevention.

Melanie S Kotys
  • Fonction : Auteur
Daniel A Herzka
  • Fonction : Auteur
Evert-Jan Vonken
  • Fonction : Auteur
Jacques Ohayon
  • Fonction : Auteur
Julie Heroux
  • Fonction : Auteur
Ahmed M Gharib
  • Fonction : Auteur
Matthias Stuber
  • Fonction : Auteur
Roderic I Pettigrew
  • Fonction : Auteur

Résumé

To enhance the clinical value of coronary magnetic resonance angiography (MRA), high-relaxivity contrast agents have recently been used at 3T. Here we examine a uniform bilateral shadowing artifact observed along the coronary arteries in MRA images collected using such a contrast agent. Simulations were performed to characterize this artifact, including its origin, to determine how best to mitigate this effect, and to optimize a data acquisition/injection scheme. An intraluminal contrast agent concentration model was used to simulate various acquisition strategies with two profile orders for a slow-infusion of a high-relaxivity contrast agent. Filtering effects from temporally variable weighting in k-space are prominent when a centric, radial (CR) profile order is applied during contrast infusion, resulting in decreased signal enhancement and underestimation of vessel width, while both pre- and postinfusion steady-state acquisitions result in overestimation of the vessel width. Acquisition during the brief postinfusion steady-state produces the greatest signal enhancement and minimizes k-space filtering artifacts.

Dates et versions

hal-00846379 , version 1 (19-07-2013)

Identifiants

Citer

Melanie S Kotys, Daniel A Herzka, Evert-Jan Vonken, Jacques Ohayon, Julie Heroux, et al.. Profile order and time-dependent artifacts in contrast-enhanced coronary MR angiography at 3T: origin and prevention.. Magnetic Resonance in Medicine, 2009, 62 (2), pp.292-9. ⟨10.1002/mrm.21997⟩. ⟨hal-00846379⟩
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